To understand the mechanism of the sequential restriction of multipotency of stem cells during development, we have established culture conditions that allow the differentiation of neuroepithelial precursor cells from embryonic stem (ES) cells. A ...
To understand the mechanism of the sequential restriction of multipotency of stem cells during development, we have established culture conditions that allow the differentiation of neuroepithelial precursor cells from embryonic stem (ES) cells. A ...
The generation of induced pluripotent stem cells (iPSCs) from somatic cells demonstrated that adult mammalian cells can be reprogrammed to a pluripotent state by the enforced expression of a few embryonic transcription factors. This discovery has ...
The generation of induced pluripotent stem cells (iPSCs) from somatic cells demonstrated that adult mammalian cells can be reprogrammed to a pluripotent state by the enforced expression of a few embryonic transcription factors. This discovery has ...
Epigenetics also refers to the changes themselves: functionally relevant changes to the genome that do not involve a change in the nucleotide sequence. Examples of mechanisms that produce such changes are DNA methylation a ...
Tumor recurrence and metastases are the major obstacles to improve the prognosis of patients with hepatocellular carcinoma (HCC).the identification of blood-based diagnostic and prognostic biomarkers that surpass existing clinicopathologic factors ...
Genetic transformation is a process that involves the introduction and expression of foreign genes in a host organism. This expression can result from the extrachromosomal, or episomal, presence of genes in nuc ...
Cell markers refer to a type of marker that is specifically expressed at a specific time in a specific cell, reflecting the growth and differentiation of cells, and can be used to identify specific cells and monitor cell growth and differentiation ...
Endothelial stem cells are one of three types of multipotent stem cells found in bone marrow. They give rise to progenitor cells, which are intermediate stem cells that lose potency, and eventually produce endothelial cells, which create ...
MicroRNA (miRNA) regulate gene expression through posttranscriptional mRNA degradation or suppression of translation. Many (pre)analytical issues remain to be resolved for miRNA screening with TaqMan Low Density Arrays (TLDA) in plasma samples, su ...
Endothelial stem cells are one of three types of multipotent stem cells found in bone marrow. They give rise to progenitor cells, which are intermediate stem cells that lose potency, and eventually produce endothelial cells, which create ...
In the year 1971 the concept of metabolic chromatography was introduced when the gas chromatography demonstrated a range of compounds present in human samples. In living systems to determine the metabolomics chromatograp ...
Genetic Syndromes & Gene Therapy is an official peer-reviewed journal for the rapid publication of innovative research covering all aspects of Gene Mapping and Gene Therapy. Genetic Syndromes, Gene Mapping & Gene Therapy with highest impac ...
Journal of Genetic Disorders is a peer-reviewed and an open access journal which aims to share the latest and advance information, studies and researches related to causes, diagnosis and treatments of molecular and genetic di ...
Genetic Syndromes & Gene Therapy Journal is one of the best open access journals that aims to publish the most complete and reliable source of information on discoveries and current developments in the mode of original articles, review article ...
Genetics encompasses study of structure and function of genes; causative factors, physiological consequences of genetic variations as well as various other aspects of heredity. Genetic studies involve in depth analysis of diverse features of DNA a ...
Hereditary spastic paraplegia (HSP) refers to a group of inherited disorders that cause weakness and stiffness of the leg muscles, which gradually gets worse over time. A person with HSP is likely to have inherited an abnormal gene from their pare ...
The Human Genome Project has transformed biology through its integrated big science approach to deciphering a reference human genome sequence along with the complete sequences of key model organisms. The project exemplifies the power, necessity an ...
Breast cancer is the most common malignancy among females. 5%–10% of breast cancer cases are hereditary and are caused by pathogenic mutations in the considered reference BRCA1 and BRCA2 genes. As sequencing technologies ...
Breast cancer is the most common malignancy among females. 5%–10% of breast cancer cases are hereditary and are caused by pathogenic mutations in the considered reference BRCA1 and BRCA2 genes. As sequencing tec ...