Modes of interactions of small ligands with CYP3A4 have been defined using the Template established in our previous studies (DMPK. 34: 113–125 2019 and 34 351–364 2019). Interactions of po ...
Carbon nanotubes (CNTs) are tubes made of carbon with diameters typically measured in nanometers. Carbon nanotubes often refer to single-wall c ...
The antifungal activities of monocytes and resident macrophages have been extensively studied. Macrophages from different species and different anatomic sites vary in their capacity to inhibit and kil ...
Human papillomaviruses (HPVs) are related with a range of various infections in people, including basic moles and genital moles. Of progressively genuine concern is the association between certain HPV types and a few malignancies, especially cervi ...
Aquatic plants are plants that have adapted to living in aquatic environments (saltwater or freshwater). They are also referred to as hydrophytes or macrophytes to distinguish them from algae and other microphytes. A macro ...
This is the process by which drugs and their metabolites exit the body, primarily via urine or feces. Drugs may also be excreted in sweat, saliva, breast milk, or exhaled air. A substance may be excreted in its altered, or metabolized, form o ...
This is the process by which drugs and their metabolites exit the body, primarily via urine or feces. Drugs may also be excreted in sweat, saliva, breast milk, or exhaled air. A substance may be excreted in its altered, or metabolized, form o ...
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by se ...
A few of the early cases had visited Huanan Seafood Wholesale Market thus the infection is thought to have a zoonotic root. The infection that caused the flare-up is known as SARSâ€CoVâ€2, a ...
A biopharmaceutical, also called a biologic(al) medical product,or biologic, is any pharmaceutical drug product synthetic in, extracted from, or semisynthesized from organic assets. Distinct from tota ...
The key to good drug design is working out and capturing the clinical spectrum of disease and the exact role a potential therapeutic target plays in the disease. In the words of the German researcher, Paul Ehrlich, known ...
Proteins are the principal targets of drug discovery. Most large pharmaceutical companies now have a proteomics-oriented biotech or academic partner or have started their own proteomics division. Common applications of proteomics in the drug indus ...
Limonoids occur naturally only in plant species of the Rutaceae and Meliaceae plant families (Manners, 2007). Limonoids are highly oxygenated modified triterpenes that are biosynth ...
caffold hopping and fragment replacement tools have proven very effective as a strategy to generate novel IP and ideas for back-up series or to replace a structural element associated with metabolic instability or unwant ...
The word bioaccumulation is used to describe the build up of chemicals in fish. Through the food chain, chemicals like PCBs, DDT, dioxins, and mercury build up in the bodies of the fish. The picture below shows how this might happen in a lake near ...
Bioaccumulation is the gradual accumulation of substances, such as pesticides or other chemicals, in an organism. Bioaccumulation occurs when an organism absorbs a substance at a rate faster than that at which the substance is lost ...
Designing clinical trials to include patient populations most likely to demonstrate a response to the therapy being studied is not a new concept. The term “enrichment” refers to the prospective incorporation ...
Traditional chemotherapy used today at clinics is mainly inherited from the thinking and designs made four decades ago when the Cancer War was declared. The potency of those chemotherapy drugs on in-vitro cancer cells is ...
Social contact can consult with: within the sociological hierarchy leading as much as social relations, an incidental social interplay among individuals. In social networks, a node (representing an ch ...
Autism, or autism spectrum disorder (ASD), refers to a vast range of conditions characterized by means of challenges with social competencies, repetitive behaviours, speech and nonverbal communique. In keeping with the c ...