Journal of antivirals & Virosomes is one of the best open access journals in the field of virology. The open access policy of the journals mainly aims at increasing the visibility and accessibility of the published quality work and thus providing the desirable researches to the readers. Antiviral Drug finding is the procedure through which numerous potential and inventive new solutions are recognized to cure HIV contamination. It fundamentally mulls over a wide extend of exploratory orders which incorporates Biology, science and drug store. Viral diseases with restricted or no medication alternatives can represent a significant worldwide wellbeing danger. A virosome is a drug or vaccine delivery mechanism consisting of unilamellar phospholipid membrane it may be mono- or bi-layered. Vesicle incorporating virus derived proteins to allow the virosomes to fuse with target cells. Virosomes are not able to replicate but are pure fusion-active vesicles. The development of safe and effective models for the delivery of any prophylactic or therapeutic agent remains an uphill task for pharmaceutical formulation developers. Drug molecules, nucleic acids, carbohydrates, proteins and a variety of other biological and chemical entities are used for attaining pharmacological benefits. However, the major challenge remains in the delivery of these agents to the specific site of action in a time-efficient manner. Among the many drug delivery systems developed, the nano scale technology of virosomes tends to present an established system of delivering the therapeutic agents to the site of pharmacological action. Virosomes are lipid bilayer, unilamellar structures that present viral protein on their surface. They are safe, biocompatible and biodegradable structures that can achieve ideal pharmacological profile once administered into the body. Tissue targeting, immune activation and potentiation are the chief advantages that make them efficient prophylactic and therapeutic agents. The review presents the biopharmaceutical applications of virosomes and the immunological and pharmaceutical considerations that make them efficient agents for targeting spatiotemporal parameters in the body. PrimeOA Publications international is the best open access publishers with expert reviewers and renowned scientists in its Editorial Board. Both editors and reviewers actively participate in the peer-review process and help in completing the review process within time.