Open acknowledgement of the human-animal bond has elevated the importance of pets to that of human beings in many owners' eyes. Most Americans view their pets as family members. In fact, studies show that more than 70 percent of pet owners think of their pets as children. Cancer is a great health concern among pet owners, and 40 percent worry about their pets having cancer regardless of the age of their pets. cancer is the number one natural cause of death in geriatric cats and dogs, and it accounts for nearly 50 percent of deaths each year. Although cancer is the leading cause of death in geriatric patients, it's also the most treatable disease when compared with congestive heart failure, renal failure, and diabetes mellitus. A trained and dedicated veterinary team is essential to compassionately care for cancer patients and clients. When a well-informed client sees a family member, whether human or non-human, stricken with cancer, s/he will embrace every possible cancer treatment. Each staff member, from receptionist to kennel attendant, must understand that s/he plays a vital role in determining a patient's quality of life. And extending a patient's good quality of life is the best reason to treat cancer. Cytotoxic drugs can be life saving for patients with cancer, but they can also be very dangerous for the staff members who must handle and administer them. The purpose of this paper is to provide general information about cancer and address concerns regarding chemotherapy administration and safety.