Toxicogenomics Innovations

Toxicogenomics Innovations

Toxicogenomics is a branch of toxicology which applies several genomic analysis techniques to determine how chemicals, both environmental and pharmaceutical agents, react on human and ecological health. It includes technologies such as genome sequence analysis, proteomics, metabolomics, and bioinformatics to detect toxic agent-induced alterations in genetic expression, protein expression, and metabolite production; moreover, effects of these alterations on phenotypic expressions at the cellular, tissue, and organism levels is also studied.Toxicogenomics is the study of the structure and function of the genome as it responds to cellular exposure to foreign agents. It combines the field of toxicology with high-throughput technologies such as transcriptomics, proteomics and metabolomics in an attempt to understand the molecular mechanisms of toxicity. Studying these mechanisms can help in building better animal and human models, with the goal of better predicting toxic response in humans. It includes technologies such as genome sequence analysis, proteomics, metabolomics, and bioinformatics to detect toxic agent-induced alterations in genetic expression, protein expression, and metabolite production; moreover, effects of these alterations on phenotypic expressions at the cellular, tissue, and organism levels is also studied.


Last Updated on: Nov 27, 2024

Global Scientific Words in Pharmaceutical Sciences