Chemistry aids in the development of healthcare, the conservation of natural sources, and the protection of the environment. Chemistry is the important technological know-how, valuable to the knowledge of other sciences and generation. Bioelectronics like bio-fuel cells, bionics etc are being used in conjunction with various biosensor devices like blood glucose meter etc. Cell signalling is the interaction of the complex systems to that governs the prime functions like cellular activities & cell coordination to perceive and react to the environmental factors. Cell signalling has great scope in studying diseases and their effective treatment. The rising field of Bioelectronics seeks to use biology in conjunction with physical science during a wider context encompassing, for instance, biological fuel cells, technology and biomaterials for IP, data storage, electronic parts and actuators. A key side is that the interface between biological materials and micro- and nano-electronics. Bio electrochemistry is a branch of chemical science and biophysical chemistry involved with topics like cell electron-proton transport, plasma membrane potentials and conductor reactions of oxidoreduction enzymes. ancient add biology has centered on finding out individual elements of cell signal pathways. Systems biology analysis helps in identifying the underlying structure of cell signal networks and the way changes in these networks might have an effect on the transmission and flow of knowledge.