Heart is a muscular organ which plays major role in pumping blood all over the body through the blood vessels of circulatory system. It is able to provide blood to the body with oxygen and nutrients and it will remove all the metabolic waste. The location of the heart is specifically in the mediastinum, the middle compartment of the thorax. Heart transplantation is the replacement of a patient's diseased or injured heart with a healthy donor heart. It is a surgical procedure performed on patients with end-stage heart diseases. Heart transplantation cannot be considered as a cure of heart disease, but it can be considered as a treatment to improve the quality of life. Patients with end-stage heart disease which threatens their life after proper medical treatment may be considered for heart transplantation. These patients should have a complete medical examination before they are undergoing for heart transplantation. There are many tests to be done, including blood tests, x rays, and tests of heart, lung, and other organ function. The results of these tests show doctors how serious the heart disease is and also about the patient's health condition towards the survival of transplant surgery. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open acess journals are indexed in SCOPUS, COPERNICUS, CAS, EBSCO and ISI.