The journal helps to gather all the relevant information on hepatitis, cirrhosis, liver cancer, alcohol damage, fatty liver, metabolic and genetic liver diseases, autoimmune liver diseases, liver transplantation and techniques, surgical complications and transplantation outcomes. The liver is a vital organ located in the right upper area of your abdomen under the ribs. Liver failure is a life-threatening condition in which there is a severe deterioration of liver function. Liver failure is caused by liver damage, which makes it difficult or impossible for the liver to function normally in processes that are critical to life and your overall health including Blood clotting, clearing the blood of toxins, fighting infection, removing waste, metabolizing medications and other substances etc. The liver is the second most commonly transplanted major organ, after the kidney, so it is clear that liver disease is a common and serious problem in this country. It is important for liver transplant candidates and their families to understand the basic process involved with liver transplants, to appreciate some of the challenges and complications that face liver transplant recipients (people who receive livers), and to recognize symptoms that should alert recipients to seek medical help.