A skin injury or wound can be open, closed, or torn. Wounds that are open run the risk of infections and closed wounds can lead to tissue damage. A soft tissue injury (STI) can occur from a sprain, strain, contusion, or overuse of a particular body area where muscles, ligaments, and tendons have become damaged. Tissue damage and infections are common following transplantation, especially in the immediate post-transplant period, and an increased risk for infection persists as a result of lifelong pharmacological immunosuppression. Tissue damage releases damage-associated molecular patterns (DAMPs), whereas infections release pathogen-associated molecular patterns (PAMPs). Both sets of molecules can stimulate innate immunity and enhance alloreactivity. The open access journals are peer reviewed scholarly journals of Biochemical engineering. The top open access Biochemical engineering journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles.