A skin injury or wound can be open, closed, or torn. Wounds that are open run the risk of infections and closed wounds can lead to tissue damage. Wound healing has become a popular sub-specialty for the doctor and allied health professional working in the laboratory or at the bedside. It is a field with many new journals and frequent congresses that publish elaborate proceedings. These have been examined for this review. A soft tissue injury (STI) can occur from a sprain, strain, contusion or overuse of a particular body area where muscles, ligaments and tendons have become damaged. Tissue damage and infections are common following transplantation, especially in the immediate post-transplant period, and an increased risk for infection persists as a result of lifelong pharmacological immunosuppression. Tissue damage releases damage-associated molecular patterns (DAMPs), whereas infections release pathogen-associated molecular patterns (PAMPs). Both sets of molecules can stimulate innate immunity and enhance alloreactivity. The impact factor of an academic journal is a scientometric index that reflects the yearly average number of citations that articles published in the last two years in a given journal received. It is frequently used as a proxy for the relative importance of a journal within its field; journals with higher impact factors are often deemed to be more important than those with lower ones.