The thyroid gland produces two hormones, tri-iodothyronine (T3) and thyroxin (T4). T3 is crafted from T4 and is the more lively hormone. Thyroid hormones influence a big range of metabolic pathways which include protein, carbohydrate and lipid metabolism. Thyroid hormones affect metabolism, mind development, respiratory, coronary heart and worried gadget features, body temperature, muscle strength, pores and skin dryness, menstrual cycles, weight, and cholesterol level. Hypothyroidism is a disorder that takes place while the thyroid gland does not make sufficient thyroid hormone to satisfy the frame’s needs. Thyroid hormone manufacturing is regulated by using thyroid-stimulating hormone (TSH), which is made by the pituitary gland within the mind. When thyroid hormone tiers in the blood are low, the pituitary releases extra TSH. When thyroid hormone tiers are excessive, the pituitary responds by dropping TSH production. Hypothyroidism is not unusual endocrinal disorder in popular populace, mainly in girls and its occurrence growth with age. It influences zero.5-2.Four% of the overall populace [1]. The hormone T3 performs a critical role in lipid metabolism by regulating genes worried in lipogenesis and lipolysis [2]. Thyroid hormones additionally maintain the preliminary level of phospholipids in cell membranes and fatty acids composition of the lipids [3]. In hyperthyroidism commonly serum degree of overall, LDL and HDL cholesterol decreases [4]. Hypercholesterolemia is found in hypothyroidism due to the increment of low density lipoprotein levels of cholesterol. High density lipoprotein cholesterol levels generally stay regular or extended [5]