A prospective, hospital based, observational study was conducted at a tertiary care hospital in Western India. Children below 12 years of age visiting the Pediatric out-patient department (OPD) and in-patient department (IPD) were included if they had clinical suspicion of thyroid dysfunction. Demographic data and clinical features of the recruited children were noted along with family history of thyroid disorders and use of iodized salt. Thyroid profile consisting of Tri-iodothyronin (T3), Thyroxin (T4) and Thyroid stimulating hormone (TSH) levels were tested in all. Investigations were also carried out to look for the cause and complications of hypothyroidism. These children were also followed up with appropriate therapy to look for response of therapy and complications to the same.