Co-infection of infectious disease and parasitic diseases in humans is a very important public drawback in co-endemic areas in developing countries. Protozoa infection, another variety of parasitic infection, is common in urban areas lacking clean water access and should end in severe deficiency disease as a consequence of chronic looseness of the bowels or eating disorder. Protozoa infection will be symptomless and should end in elevated levels of cytokines like interferon-γ (IFN-γ), a important treater within the host immune reaction to Mycobacterium tuberculosis. phthisis and parasitic diseases were shown to be risk factors for every alternative. Co-infection might considerably inhibit the host’s system, increase medication medical aid intolerance and be damaging to the prognosis of the disease; additionally, infection with parasitic diseases will alter the protecting immune reaction to Bacilli Calmette-Guerin vaccination against Mycobacterium tuberculosis.Indeed, this study urged that because of difficult immune conditions of TB patients with immunological disorder disorders, this cluster of patients ar at higher risk of infection by enteral parasites.