Substandard medicines are the products in which composition and ingredients do not meet the correct scientific specifications and may occur as a result of negligence, human error etc.Counterfeit medicines are fraudulently mislabeled with respect to identity and/or source. High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field.