Malignant rhabdoid tumor is a rare childhood tumor that commonly starts in the kidneys but also can occur in other soft tissues or in the brain, where it is referred to as atypical teratoid rhabdoid tumor (ATRT). Malignant rhabdoid tumor occurs most commonly in infants and toddlers; the average age of diagnosis is 15 months old. There are about 20 to 25 new cases of malignant rhabdoid tumor diagnosed each year in the United States. Cells from malignant rhabdoid tumors in children can spread (metastasize) to other areas of the body. Dana-Farber/Boston Children’s is a world-leading center in the research and treatment of rhabdoid tumors. Our vibrant program of basic and translational research into rhabdoid tumors is uncovering new opportunities to improve the care of children with malignant rhabdoid tumor. Our multidisciplinary treatment approach ensures in-depth discussion of each child and personalized treatment plans for every patient. There is no clear cause of malignant rhabdoid tumor.