Regional Anesthesia is the technique that involving patients' body insensate to surgical stimuli by rendering a small portion. Regional anesthesia compared to general anesthesia. Regional anesthetics get in reducing pain, thereby facilitating surgical procedures. Regional anesthetics comparatively are safer than general or systemic anesthetics; therefore, they are used whenever possible. Ultrasound imaging has became a popular technique to perform regional anesthesia. Regional anesthetics have been associated with less post-operative pain and less nausea. Regional anesthesia is particularly appealing to patients undergoing orthopedic procedures.