Pulmonary Hypertension (PH) is a disorder formed by various diseases that have pathological similarities, therefore diverge in pathophysiology and prognosis. Clinically, it is characterized by dyspnea, chest pain and syncope, causing progressive limitation, right-heart failure, and death. Histopathologically occurs pulmonary vascular remodeling, with subsequent increase of resistance, and in situ thrombosis. Scholarly peer review is the process of subjecting an author's scholarly work, research, or ideas to the scrutiny of others who are experts in the same field, before a paper describing this work is published in a journal. The work may be accepted, considered acceptable with revisions, or rejected. Peer review requires a community of experts in a given (narrowly defined) field, who are qualified and able to perform reasonably impartial review. Pulmonary hypertension occurs for many reasons, most commonly as a complication of cardiopulmonary or systemic disease. The World Health Organization (WHO) has classified PH into five groups on the basis of distinct pathophysiology, pulmonary hemodynamics and management strategies WHO group 1 refers to pulmonary arterial hypertension, characterized by the progressive remodeling, narrowing and obliteration of small pulmonary arteries due to proliferation of smooth muscle and endothelial cells, vascular wall inflammation, and fibrosis