The method where mass spectrometry is applied to examine proteins is known as Protein mass spectrometry. There are two stages utilized for portraying proteins: In the initial step, proteins are ionized by electrospray ionization (ESI) or network helped laser desorption/ionization (MALDI). In the second, proteins are acquainted with a mass analyzer and enzymatically processed into littler peptides utilizing a protease. Toward the end peptides are brought into the mass spectrometer and distinguished by peptide mass fingerprinting or couple mass spectrometry. Insightful diary is a companion checked on diary in which grant identifying with a specific scholarly control is distributed. Insightful diaries fill in as gatherings for the presentation and introduction for examination of new research, and the evaluate of existing exploration.