Potato leafroll virus (PLRV) is a member of the genus Polerovirus and family Luteoviridae. The phloem limited positive sense RNA virus infects potatoes and other members of the family Solanaceae. PLRV was first described by Quanjer et al. in 1916.PLRV is transmitted by aphids, primarily the green peach aphid, Myzus persicae. PLRV is one of the most important potato viruses worldwide but particularly devastating in countries with limited resources and management. It can be responsible for individual plant yield losses of over 50%. One estimate suggests that PLRV is responsible for an annual global yield loss of 20 million tons. Symptoms include chlorosis, necrosis and leaf curling.Potato leafroll virus infects other hosts including moonflower, Datura stramonium causing interveinal necrosis and hairy nightshade, Solanum villosum causing chlorosis, leafroll and leathery texture of leaves. Husk tomato, Physalis floridana symptoms include chlorosis, rolling of the leaves and stunting. PLRV infects many other plants in the family Solanacea and can also infect some non-solanaceous plants.