Pharmaceutical Care could be a patient-centered, outcomes orientating pharmacy follow that needs the pill roller to figure as one with the patient and therefore the patient's alternative tending suppliers to push health, to forestall unwellness, and to assess, monitor, initiate, and modify medication use to assure that drug medical aid. Torii Pharmaceutical Corporation, Tokyo, Japan) and 9 custom-made reagents. One-hundred-and-sixty-seven patients were females (78.8%) and 45 patients were males (21.2%). A total of 148 patients (69.8%) had one or more positive patch test reactions. The most common allergens were nickel (25.0%), palladium (24.4%), chromium (16.7%), cobalt (15.9%) and stannum (12.5%). Typical allergic symptoms and diagnoses were Pustulosis palmaris et plantaris, lichen planus, stomatitis and contact dermatitis. This study indicates that dentists and dental researchers should be concerned about the allergenic potential of dental metal materials.