Peyronie’s Disease Scientific Journals

Peyronie’s Disease Scientific Journals

A condition characterized by hardening of the PENIS due to the formation of fibrous plaques on the dorsolateral aspect of the PENIS, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both.A condition characterized by hardening of the PENIS due to the formation of fibrous plaques on the dorsolateral aspect of the PENIS, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both. Peyronie’s disease (PD) due to its high efficacy and low morbidity. Among the surgical procedures, penile plication (PP) can be offered to men who have adequate erectile function and penile length (>13 cm), with a curvature <60° and a predicted shortening of maximum 20% of the penis. The aim of this paper is to review the new developments that have emerged in the last years about the use of PP in patients with PD. A nonsystematic review of the literature was carried out searching in the PubMed and EMBASE databases from January 01, 2009 to April 01, 2019 including the words ‘Peyronie’, ‘penile curvature’, ‘penile induration’, ‘plication’, and ‘plicature’. Peyronie disease (Peyronies), also known as Morbus Peyronie or Induratio Penis Plastica (IPP), results in a bent penis due to collagen accumulation and tissue contraction. Possibly this is due to a genetic disposition. IPP can appear quickly while Dupuytren's contracture typically develops over 5 - 10 years. It also seems that self-healing, i.e. spontaneous healing without treatment, is more frequent for IPP than for Dupuytren or Ledderhose (though self-healing cases might possibly not have been Peyronies). About 15 - 20 percent of patients suffering from Peyronie's also suffer from Dupuytren's contracture  thus supporting the concept of a common or related root cause.


Last Updated on: Nov 26, 2024

Global Scientific Words in Clinical Sciences