Hepatitis B infection (HBV) contamination in a pregnant lady represents a genuine hazard to her newborn child during childbirth. Without postexposure immunoprophylaxis, around 40% of newborn children destined to HBV-contaminated moms in the United States will create constant HBV disease, roughly one-fourth of whom will in the long incredible ceaseless liver malady. Perinatal HBV transmission can be forestalled by recognizing HBV-contaminated (i.e., hepatitis B surface antigen [HBsAg]-positive) pregnant ladies and giving hepatitis B resistant globulin and hepatitis B immunization to their newborn children inside 12 hours of birth. Forestalling perinatal HBV transmission is an essential piece of the national technique to dispose of hepatitis B in the United States. National rules require the accompanying: Universal screening of pregnant ladies for HBsAg during every pregnancy Screening all HBsAg-positive pregnant ladies for HBV DNA to direct the utilization of maternal antiviral treatment during pregnancy. AASLD recommends maternal antiviral treatment when HBV DNA is >200,000 IU/mCase the executives of HBsAg-positive moms and their newborn children .Provision of immunoprophylaxis for newborn children destined to tainted moms, including hepatitis B immunization and hepatitis B resistant globulin inside 12 hours of birth .Routine inoculation of all babies with the hepatitis B immunization arrangement, with the principal portion managed inside 24 hours of birth This program gives assets and specialized help to neighborhood wellbeing offices for perinatal hepatitis B counteraction and to give reconnaissance to perinatal hepatitis B cases.