Safety and efficacy assessment is important in medical practices. Clinical trials are known as maintaining a set of regulations and procedures that determine the safety and effectiveness of medications, devices, diagnostic products and treatment regimens intended for human use. Regulations and guidelines are maintained globally for such issues along with testing of novel drugs, new medical procedure, new medical devices etc., where animal trials are followed by human trials. This peer reviewed journal covers a broad aspect of Clinical trials, Clinical practice guidelines, Clinical research and bioethics, Pre-clinical trials, Randomized trials, Protocols and other related topics justifying the title of the Journal.