Pathogenesis is defined because the origination and development of a disease. Insights into disease etiology and progression, the 2 major aspects of pathogenesis, are paramount within the prevention, management and treatment of varied diseases. sorts of pathogenesis include microbial infection, inflammation, malignancy and tissue breakdown. for instance , bacterial pathogenesis is that the mechanism by which bacteria cause infectious illness. Most diseases are caused by multiple processes. Pathogenesis is that the process by which an infection results in disease. Pathogenic mechanisms of viral disease include (1) implantation of virus at the portal of entry, (2) local replication, (3) spread to focus on organs (disease sites), and (4) spread to sites of shedding of virus into the environment.