Parkinson's disease is a cerebrum issue that prompts shaking, solidness, and trouble with strolling, equalization, and coordination. Parkinson's ailment happens when nerve cells, or neurons, in a region of the cerebrum that controls development become debilitated and additionally pass on. Parkinson’s disease affects the nerve cells in the brain that produce dopamine. Parkinson’s disease symptoms include muscle rigidity, tremors, and changes in speech and gait. After diagnosis, treatments can help relieve symptoms, but there is no cure. Parkinson’s disease is a progressive neurological disorder. The first signs are problems with movement. Smooth and coordinated muscle movements of the body are made possible by a substance in the brain called dopamine. Dopamine is produced in a part of the brain called the “substantia nigra.” In Parkinson’s, the cells of the substantia nigra start to die. When this happens, dopamine levels are reduced. When they have dropped 60 to 80 percent, symptoms of Parkinson’s start to appear. There’s currently no cure for Parkinson’s, a disease which is chronic and worsens over time. More than 50,000 new cases are reported in the United States each year. But there may be even more, since Parkinson’s is often misdiagnosed. The exact cause of Parkinson’s is unknown. It may have both genetic and environmental components. Some scientists think that viruses can trigger Parkinson’s as well. Low levels of dopamine and norepinephrine, a substance that regulates dopamine, have been linked with Parkinson’s. Abnormal proteins called Lewy bodies have also been found in the brains of people with Parkinson’s. Scientists don’t know what role, if any, Lewy bodies play in the development of Parkinson’s.