natural chemistry is crucial because of the fact it's far they have a look at of life and all of the chemical reactions related to existence. several careers exercise a know-how of organic chemistry, along with medical doctors, veterinarians, dentists, pharmacologists, chemical engineers, and chemists.
Characterization of organic compounds, Structure and bonding, Synthetic organic chemistry, Synthesis of chemical reagents, Functional group reactions, Chemical reactions involving organic compounds, Organic synthesis and catalysis, Electronic organic chemistry, Green chemistry, Microwave chemistry, Fullerenes, Stereochemistry, Spectroscopy studies, Organometalic chemistry, Organic geochemistry, Free radicals chemistry,Photo chemistry, Bioorganic chemistry, Physical and theoretical organic chemistry, Natural products chemistry, Petroleum organic chemistry, Quantum chemistry, Synthesis of biologically active compounds, Food and Agriculture organic chemistry.
This review is a compilation of the green synthetic methods used in the synthesis of coumarin derivatives. Coumarins are a class of compounds with a pronounced wide range of biological activities, which have found their application in medicine, pharmacology, cosmetics and food industry. Their biological activity and potential application are highly dependent on their structure. Therefore, many researchers have been performing the synthesis of coumarin derivatives on a daily basis. High demands for their synthesis often result in an increased generation of different waste chemicals. In order to minimize the utilization and generation of toxic organic substances, green synthetic methods are applied in this manner. These methods are getting more attention in the last few decades. Green chemistry methods cover a wide range of methods, including the application of ultrasound and microwaves, ionic liquids and deep eutectic solvents, solvent-free synthesis, mechanosynthesis and multicomponent reactions. All typical condensation reactions for coumarin synthesis like Knoevenagel, Perkin, Kostanecki-Robinson, Pechmann and Reformansky reactions, have been successfully performed using these green synthetic methods.