Nanotechnology is manipulation of matter on an atomic, molecular and supramolecular scale. The earliest widespread description of nanotechnology referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macroscale products, also now referred to as molecular nanotechnology. A more generalized description of nanotechnology was subsequently established by the National Nanotechnology Initiative which defines nanotechnology as the manipulation of matter with at least one dimension sized from 1 to 100 nanometers.