the process through which healthy cells become transformed into cancer cells. It is characterized by a series of genetic and cellular changes, including oncogene activation, that lead the cell to divide in an uncontrolled manner. Oncogenesis or cancer formation is the expression of impaired cellular events in the favor of uncontrolled cell growth and proliferation. Carcinogenesis or oncogenesis is a process by which normal cells are transformed into cancer cells. OncoGenesis is addressing the tremendous, unmet clinical need for an easy to use and accurate screening of women for cervical cancer. An oncogene is a gene that has the potential to cause cancer. In tumor cells, these genes are often mutated, or expressed at high levels. Most normal cells will undergo a programmed form of rapid cell death (apoptosis) when critical functions are altered and malfunctioning. Cytoplasmic tyrosine kinases – Examples of these oncogenes include the Abl gene in chronic myeloid leukemia (the Philadelphia chromosome) and the Src family, Syk-ZAP-70 family and BTK family of tyrosine kinases. Cytoplasmic serine/threonine kinases – include Raf kinase and cyclin-dependent kinases. A gene that is a mutated (changed) form of a gene involved in normal cell growth. Oncogenes may cause the growth of cancer cells.