An oncogene is a mutated gene that contributes to the development of a cancer. In their normal, unmutated state, onocgenes are called proto-oncogenes. The process through which healthy cells become transformed into cancer cells. It is characterized by a series of genetic and cellular changes, including oncogene activation, that lead the cell to divide in an uncontrolled manner. Oncogenesis or cancer formation is the expression of impaired cellular events in the favor of uncontrolled cell growth and proliferation. Carcinogenesis or oncogenesis is a process by which normal cells are transformed into cancer cells. OncoGenesis is addressing the tremendous, unmet clinical need for an easy to use and accurate screening of women for cervical cancer. Mutations may cause proto-oncogenes to become oncogenes, disrupting normal cell division and causing cancers to form. . Most normal cells will undergo a programmed form of rapid cell death (apoptosis) when critical functions are altered and malfunctioning. Cytoplasmic tyrosine kinases – Examples of these oncogenes include the Abl gene in chronic myeloid leukemia (the Philadelphia chromosome) and the Src family, Syk-ZAP-70 family and BTK family of tyrosine kinases. Cytoplasmic serine/threonine kinases – include Raf kinase and cyclin-dependent kinases.