Neurosyphilis is a bacterial infection caused when one has a direct contact with syphilis sores. It is a sexually transmitted disease, hence associated with HIV. The noticeable symptoms of this disease are headache, nausea, vomiting and impairment of auditory and olfactory organs. Nerosyphilis is a condition in which brain gets infected. The treatment includes penicillin injection. Persons with syphilis are significantly prone to HIV infections. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.