Nanopharmacology involves the application of nanoparticles to improve efficacy or pharmacokinetics of drugs to their target site and to minimize their side effects. Nanopharmacology in simple words involves packaging of old and new drugs such as chemo, immuno, nucleic acids or small molecules in nanoparticles. Infact this strategy of packaging old drugs inside the nanoparticles is the ultimate solution to growing global threat on patients’ resistance to antibiotics and chemotherapy. Nanotechnology is concerned with materials and systems whosestructure and components exhibit novel and significantly improved physical, chemical, and biological properties, phenomena, and processes because of their nanoscale size. Nanomaterials differ significantly from other materials due to the following two major principal factors: the increased surface area and quantum effects. These factors can enhance properties such as reactivity, strength, electrical characteristics, and in vivo behavior. As the particle size decreases, a greater proportion of atoms are found at the surface compared to inside. Thus, a nanoparticle has a much greater surface area per unit mass compared with larger particles, leading to greater reactivity.