Nanodrug delivery are designed to beat these challenges thanks to the event and fabrication of nanostructures. It has been reported that, nanostructures have the power to guard drugs from the degradation within the alimentary canal , the technology also allows target delivery of medicine to varied areas of the body. The technology enables the delivery of medicine that are poorly water soluble and may provide means of bypassing the liver, thereby preventing the primary pass metabolism. Nanotechnology increases oral bioavailability of medicine thanks to their specialized uptake mechanisms like absorptive endocytosis and are ready to remain within the blood circulation for a extended time, releasing the incorporated drug during a controlled fashion resulting in less plasma fluctuations and minimizing side-effects. Open Access articles are immediately, freely available on their internet site , a model mostly funded by charges paid by the author (usually through a search grant).