Myxoid leiomyosarcoma is an uncommon variation of uterine leiomyosarcoma described by insipid cellularity, myxoid network and forceful conduct . Leiomyosarcoma is the most widely recognized uterine sarcoma and records for 1% of uterine malignancies. Hardly any instances of myxoid leiomyosarcoma were accounted for in the writing and the information was deficient for definitive epidemiological examinations with respect to the rate and pervasiveness of this pathology. The prior leiomyomas doesn't speak to a hazard factor for this danger. The revealed a five-year endurance pace of 15-35% with a progressively great guess for patients indicating stage I tumors and for premenopausal females. In this paper is introduced an uncommon instance of uterine myxoid leiomyosarcoma with its histological and immunohistochemical particularities.