Musculoskeletal conditions are the leading contributor to disability worldwide, with low back pain being the single leading cause of disability globally.Musculoskeletal conditions and injuries are not just conditions of older age; they are prevalent across the life-course. Between one in three and one in five people(including children) live with a musculoskeletal pain condition.Musculoskeletal conditions significantly limit mobility and dexterity, leading to early retirement from work, reduced accumulated wealth and reduced ability to participate in social roles.The greatest proportion of non-cancer persistent pain conditions is accounted for by musculoskeletal conditions.