Fecal microbiota transplantation (FMT) is an imbuement in the colon, or the conveyance through the upper gastrointestinal tract, of stool from a solid contributor to a beneficiary with an illness accepted to be identified with the undesirable gut microbiome. FMT has been effectively used to treat intermittent Clostridium difficile contamination (CDI). The transient achievement of FMT in CDI has prompted examinations of its application to other gastrointestinal issues and extra-intestinal sicknesses with assumed gut dysbiosis. In spite of the promising consequences of FMT in these conditions, a few hindrances remain, including deciding the attributes of a solid microbiome, guaranteeing the wellbeing of the beneficiary concerning long haul results, satisfactory checking of the beneficiary of fecal material, accomplishing great control, and keeping up sensible expenses. Thus, building up uniform conventions for stool arrangement, finding the best methods of FMT organization, keeping up huge databases of givers and beneficiaries, and guaranteeing that oral ingestion is equal to the more generally acknowledged colonoscopic implantation are issues that should be tended to.