Mesenchyme stem cells (MSCs) are multipotent stem cells determined in bone marrow which can be critical for making and repairing skeletal tissues, inclusive of cartilagebone and the fats located in bone marrow. those aren't to be confused with haematopoietic (blood) stem cells which might be also discovered in bone marrow and make our blood.Mesenchymal stem cells are characterized morphologically with the aid of a small cellular body with some cell approaches which can be long and thin. The cell body includes a huge, round nucleus with a outstanding nucleolus, which is surrounded by way of finely dispersed chromatin particles, giving the nucleus a clear look. The remainder of the mobile body includes a small quantity of Golgi equipment, rough endoplasmic reticulum, mitochondria and polyribosomes. The cells, which might be lengthy and thin, are widely dispersed and the adjoining extracellular matrix is populated with the aid of some reticular fibrils but is devoid of the opposite kinds of collagen fibrils ,Bone marrow turned into the authentic source of MSCs,and still is the maximum regularly applied. these stem cells do now not make a contribution to the formation of blood cells and so do no longer explicit the hematopoietic stem cell marker CD34. they may be sometimes known as bone marrow stromal stem cells,MSCs have a incredible potential for self-renewal even as retaining their multipotency. .