The current study addressed the issue of working memory (WM) impairment in relapsing-remitting multiple sclerosis (RRMS) patients, employing the definition of WM based on Alan Baddeleyâs model in cognitive psychology. Built on previous existing models of short-term memory, this structural model proposed the existence of two subsystems that are dependent upon a third attentionally limited control component, the central executive. According to Baddeley, the phonological loop subsystem deals with verbal and acoustic information while the visuospatial sketchpad processes visual and spatial material. More recently, a fourth subsystem, the episodic buffer, has been added and is suggested to relate WM with long-term memory by integrating information from multiple sources.