The aim of the Medicinal Chemistry Journal Review is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines. Medicinal Chemistry Journal Review covers all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural marketing research and structure-activity relationship studies. Medicinal Chemistry Journal Review is an important journal for each medicinal and pharmacologist who wishes to be kept informed and up-to-date with the newest and most vital developments.
The Medicinal Chemistry Journal publishes studies that contribute to an understanding of the connection between molecular structure and biological activity or mode of action.
Some specific areas that are appropriate include the following:
Design, synthesis, and biological evaluation of novel biologically active compounds, diagnostic agents, or labeled ligands employed as pharmacological tools. Molecular modifications of reported series that cause a significantly improved understanding of their structure-activity relationships (SAR). Routine extensions of existing series that don't utilize novel chemical or biological approaches or don't add significantly to a basic understanding of the SAR of the series will normally not be accepted for publication. Structural biological studies (X-ray, NMR, etc.) of relevant ligands and targets with the aim of investigating molecular recognition processes within the action of biologically active compounds. Molecular biological studies (e.g., site-directed mutagenesis) of macromolecular targets that cause an improved understanding of molecular recognition.