Mass Spectrometry, also referred to as mass spec, is an analytical technique becoming increasingly important in bioscience research. This article will introduce you to this technique, how it works, and how it could be useful to you in your research. So, let’s get started with your introduction to mass spectroscopy. In a nutshell, mass spectrometry accurately measures the mass of different molecules within a sample. Even large biomolecules like proteins are identifiable by mass, which means that biologists can perform some very interesting experiments using mass spectroscopy, potentially adding a new dimension to your research. Mass spectrometry is one of the most powerful modern physical-chemical methods for identifying compounds, and for studying their structure and reactivity. Recent developments in ionization and ion separation have made it possible to apply this technique to a wide range of individual compounds and mixtures. Mass spectrometry has a wide range of applications because of its sensitivity and selectivity. Mass spectrometers are used to solve a variety of analytical problems, ranging from molecular weight and elemental composition determination, to the characterization of structures of complex bio-organic molecules and the analysis of polymers. Isotope analyses can be performed on inorganic and organic substances. Mass spectrometry is the method of choice for many environmental, industrial, clinical, and forensic analyses. The determination of atom connectivities in simple and complex molecules, the elucidation of amino-acid sequences, and other structural applications have become a routine application of this technique. Importantly, mass spectrometry is a key technique in the expanding field of proteomics.