A number of enzymes such as amylase, caseinase, lipase, gelatinase, and DNases have been discovered from microbes isolated from extreme marine environments. Such enzymes are thermostable, tolerant to a varied range of pH and other harsh conditions required in industrial applications.Moreover, some examples of enzymes from marine origin that are or may be of relevance for biotransformation processes are presented. The evolution prompted the marine microorganisms to generate multifarious enzyme systems to adapt to the complicated marine environments.A marine enzyme may be a unique protein molecule not found in any terrestrial. organism or it may be a known enzyme from a terrestrial .Enzymes known so far from marine microorganisms include α-Amylase, α-glucosidase, pullulanase, Cyclomaltodextrin-glucanotransferase, Agarase, alginate.