A local anesthetic is a drug that causes reversible local anesthesia, generally for the aim of having a local analgesic effect that is, inducing absence of pain sensation, although other local senses are often affected as well. Local Anesthetics are widely used in clinical use for pain relief in situations ranging from dental procedures to gynecological interventions. In therapeutic concentrations, Local Anesthetics reversibly block nerve transmission, cause local loss of feeling while relieving local pain and preventing muscle activity in the process. They may be administered by injection, continuous infusion, and some by topical application.