Leptospirosis is a relatively rare bacterial infection that affects people and animals. It can pass from animals to humans when an unhealed break in the skin comes in contact with water or soil where animal urine is present.Several species of the Leptospira genus of bacteria cause leptospirosis. It can progress to conditions such as Weil’s disease or meningitis, which can be fatal.Without treatment, Leptospirosis can lead to kidney damage, meningitis (inflammation of the membrane around the brain and spinal cord), liver failure, respiratory distress, and even death.More than ten genetic types of Leptospira cause disease in humans. Both wild and domestic animals can spread the disease, most commonly rodents.The bacteria are spread to humans through animal urine, or water and soil contaminated with animal urine, coming into contact with the eyes, mouth, nose or breaks in the skin.In developing countries, the disease occurs most commonly in farmers and low-income people who live in areas with poor sanitation.[5] In developed countries, it occurs during heavy downpours and can affect those involved in outdoor activities in warm and wet areas.[5] Diagnosis is typically by testing for antibodies against the bacteria or finding bacterial DNA in the blood.[5]