Kidneys are a pair of organs located toward your lower back. One kidney is on each side of your spine. They filter your blood and remove toxins from your body. Kidneys send toxins to your bladder, which your body later removes, toxins during urination. Insufficient blood flow to the kidneys can cause acute perennial kidney failure. The kidneys can’t filter toxins from the blood without enough blood flow. This type of kidney failure can usually be cured once your doctor determines the cause of the decreased blood flow. When there isn’t enough blood flowing to the kidneys for an extended period of time, the kidneys begin to shrink and lose the ability to function. Measuring urine output is one of the simplest tests to help diagnose kidney failure. For example, low urinary output may suggest that kidney disease is due to a urinary blockage, which multiple illnesses or injuries can cause. It’s still possible to manage and slow progression by maintaining a healthy lifestyle. This includes eating a balanced diet, regularly exercising, and not using tobacco products. Maintaining a healthy weight is important, too. The same lifestyle approaches that helped in stage 1 are still used in stage 2. Also talk with your doctor about other risk factors that could make the disease progress more rapidly. These include heart disease, inflammation, and blood disorders. Citations are important for a journal to get impact factor. Impact factor is a measure reflecting the average number of citations to recent articles published in the journal. The impact of the journal is influenced by impact factor, the journals with high impact factor are considered more important than those with lower ones. This information can be published in our peer reviewed journal with impact factors and are calculated using citations not only from research articles but also review articles (which tend to receive more citations), editorials, letters, meeting abstracts, short communications, and case reports.