Chemical engineering is a branch of engineering that uses principles of chemistry, physics, mathematics, biology, and economics to efficiently use, produce, design, transport and transform energy and materials. The work of chemical engineers can range from the utilisation of nano-technology and nano-materials in the laboratory to large-scale industrial processes that convert chemicals, raw materials, living cells, microorganisms, and energy into useful forms and products.Chemical engineers are involved in many aspects of plant design and operation, including safety and hazard assessments, process design and analysis, modeling, control engineering, chemical reaction engineering, nuclear engineering, biological engineering, construction specification, and operating instructions.Chemical engineers typically hold a degree in Chemical Engineering or Process Engineering. Practising engineers may have professional certification and be accredited members of a professional body. Such bodies include the Institution of Chemical Engineers (IChemE) or the American Institute of Chemical Engineers (AIChE). A degree in chemical engineering is directly linked with all of the other engineering disciplines, to various extents. Chemical engineering emerged upon the development of unit operations, a fundamental concept of the discipline of chemical engineering. Most authors agree that Davis invented the concept of unit operations if not substantially developed it. He gave a series of lectures on unit operations at the Manchester Technical School (later part of University of Manchester Institute of Science and Technology and now the University of Manchester) in 1887, considered to be one of the earliest such about chemical engineering. Three years before Davis' lectures, Henry Edward Armstrong taught a degree course in chemical engineering at the City and Guilds of London Institute. Armstrong's course failed simply because its graduates were not especially attractive to employers. Employers of the time would have rather hired chemists and mechanical engineers. Courses in chemical engineering offered by Massachusetts Institute of Technology (MIT) in the United States, Owens College in Manchester, England, and University College London suffered under similar circumstances.