BMC Systems Biology is an open access journal publishing original peer-reviewed research articles in experimental and theoretical aspects of the function of biological systems at the molecular, cellular or organismal level, in particular those addressing the engineering of biological systems, network modelling, quantitative analyses, integration of different levels of information and synthetic biology Diary of Systems Biology Research (JSBR) diary is focused on everybody working in the displaying and revelation of developing properties in complex organic systems. Additionally, it looks for researchers relating the structure and elements of living life forms with their physiology and phenotypic characteristics for the comprehension of the entirety. Notwithstanding the greatest unique articles covering the whole field, each issue incorporates opportune surveys of key essential examination papers and points in Systems Biology. Additionally, the Editors look for the distribution of reports on developing patterns in the incorporation of hypothetical models, computational examination and experimental information, as a structure for seeing any size of natural association, running from single cells to biological systems. The Editorial Committee effectively seeks after to be a main wellspring of fundamental information through advancing greatness and headway in Systems Biology, Quantitative and Predictive Physiology, and Medicine. The diary energizes unique exploration, master audit of Systems Biology at the bleeding edge of an increasingly all encompassing way to deal with understanding the dynamic and complex nature of living systems better. Additionally, gives understanding into framework level methodologies of natural examination, while potentiating a change in the way to deal with the examination of crucial and more extensive organic systems. JSBR is especially keen on getting compositions that reports of unique examinations, and excellent audits intriguing to a global crowd.