The vessels of the neck ultrasound showed a diffuse bilateral carotid intimo-medial thickening without hemodynamic effect. The lumbar puncture brought back a clear liquid, with 23 items (to lymphocytic predominance) and 0.93 g/l of content as the FTA (Fluorescent Treponemal Antibody) was negative. Serology positive HIV2, the CD4 count at 263 viral load: 48.000 copies/ ml Antigen Hbc (negative), syphilitic serology and Antigen Hbs (negative). The rest of the balance of risk and Etiologic factors was normal. Before these clinical disorders of the patient and the check carried out, we had retained the diagnosis of recurrence of stroke on high blood pressure and field of immunosuppression (HIV 2). The patient had a treatment with acetylsalicylic acid, antihypertensive (inhibitor of the enzyme conversion, combined with a calcium inhibitor), enoxaparin sodium 4000 IU anti-Xa per day, physiotherapy, Ceftriaxone 2 g per day, strict monitoring of vital parameters. She had benefited from the association zidovudine lamivudine (Combivir®) in the dose of one tablet twice a day, but she was more back until her episode of stroke. After counseling on compliance the same antiretroviral treatment has been extended. The patient was still not regularly his treatment.