Cardiovascular disease (CVD) ranks first as a cause of death in the United States and globally. Among PLWH, mortality attributable to CVD is growing in importance. The proportion of deaths attributable to CVD in PLWH in the United States more than doubled between 1999 and 2013, from 2.0% to 4.6%.Extensive evidence shows that HIV infection is an independent risk factor for coronary artery disease and, to a lesser extent, heart failure (HF). Information on the link between HIV infection and other cardiovascular conditions such as stroke, peripheral artery disease (PAD), or atrial fibrillation (AF), however, remains scarce. Elucidating the impact of HIV infection on a wide range of CVDs will contribute to a more comprehensive characterization of the burden of nonâ€communicable disorders in PLWH, informing their specific needs for control of CVD risk factors. This is of particular importance given recent findings showing that interventions on traditional cardiovascular risk factors could prevent a substantial proportion of CVD in PLWH. In addition, this information can provide support for future work exploring the pathways linking HIV infection and CVD. Thus, we evaluated the association of HIV infection with specific CVDs in a large healthcare administrative database in the United States.