High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years. Pancreas is one of the important organs of human body, which is responsible of producing the hormones, insulin being one of them. Insulin is the hormone that unlocks the cells of the body so that they the sugar from the food facilitate from the blood to there to be used up as the energy. Insulin resistance occurs when body supplies not enough insulin for the body glucose to get converted resulting in the high blood sugar that remains unconverted in the body. There are various medications to cure this case, some related to help the insulin to convert the sugar properly, others working on producing more insulin for the body for the same cause. Studies show that insulin resistance may arise due to obesity and further results into increased inflammation. Brain fog, high blood sugar, increased dizziness are few symptoms to check the presence of insulin resistance