Interruption or suppression of the expression of a gene at transcriptional or translational levels. There are three different types of gene silencing: Transcriptional, Post transcriptional and meiotic. Gene silencing is used in research areas of Antisense oligonucleotides, ribozymes,RNA interference. PrimeOA Publications International is one of the leading Open Access Publishers which is running 700+ peer-reviewed journals. PrimeOA Publications through its Open Access Initiative is committed to make genuine and reliable contributions to the scientific community. It follows an Open Access publication model that enables the dissemination of research articles to the global community free of cost. Journal of Advanced Techniques in Biology and Medicine is one of the peer review journals, globally maiden journal with the wide range of area that deals with diagnosis, treatment, prevention of disease and other damage to the body or mind. Peer review refers to the work done during the screening of submitted manuscripts and funding applications. This process encourages authors to meet the accepted standards of their discipline and reduces the dissemination of irrelevant findings, unwarranted claims, unacceptable interpretations, and personal views.