Journal of Computational Systems Biology (JCSB) is an open access, peer-reviewed journal publishing articles related to structure prediction of proteins and protein complexes, molecular simulation, systems biology, genomics, protein design, and drug discovery. JCSB aim’s to build up a comprehension of issues connected with organically significant computational models and serves mainstream researchers by providing free online access to high-quality articles. The persistence behind this journal is to give top-notch scientific resources for academics interested in the fields of Computational Biology, and the journal is seeking submissions of original investigative research and clinical work on biological databases and bio-algorithms, new concepts in systems biology, etc.